Risk factors of skin cancer

Risk factors

Factors that increase your risk of basal cell carcinoma include:

• Chronic sun exposure. A lot of time spent in the sun — or in commercial tanning beds — increases the risk of basal cell carcinoma. The threat is greater if you live in a sunny or high-altitude location, both of which expose you to more UV radiation. Severe sunburns also increase your risk.
• Radiation therapy. Radiation therapy to treat acne or other skin conditions may increase the risk of basal cell carcinoma at previous treatment sites on the skin.
• Fair skin. The risk of basal cell carcinoma is higher among people who freckle or burn easily or who have very light skin, red or blond hair, or light-colored eyes.
• Increasing age. Because basal cell carcinoma often takes decades to develop, the majority of basal cell carcinomas occur in older adults. But it can also affect younger adults and is becoming more common in people in their 20s and 30s.
• A personal or family history of skin cancer. If you've had basal cell carcinoma one or more times, you have a good chance of developing it again. If you have a family history of skin cancer, you may have an increased risk of developing basal cell carcinoma.
• Immune-suppressing drugs. Taking medications that suppress your immune system, such as anti-rejection drugs used after transplant surgery, significantly increases your risk of skin cancer.
• Exposure to arsenic. Arsenic, a toxic metal that's found widely in the environment, increases the risk of basal cell carcinoma and other cancers. Everyone has some arsenic exposure because it occurs naturally. But some people may have higher exposure if they drink contaminated well water or have a job that involves producing or using arsenic.
• Inherited syndromes that cause skin cancer. Certain rare genetic diseases can increase the risk of basal cell carcinoma, including nevoid basal cell carcinoma syndrome (Gorlin-Goltz syndrome) and xeroderma pigmentosum.